391 results
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... diuretics - Thiazides ... Furosemide - Thiazide ... panitumumab) #Drugs #hypokalemia
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... ß-Adrenergic agonists, Hypokalemic ... congenital), Thyrotoxic hypokalemic ... diuretics, and thiazide-like ... syndrome (mimics thiazide
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Inherited (AR) hypokalemic ... affecting the thiazide-sensitive ... gene - Encodes thiazide-sensitive ... patients with thiazide ... • Unexplained hypokalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... paralysis/familial hypokalemic ... Bartter's syndrome • Thiazide ... Liddle's syndrome #Hypokalemia
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Absent: Loop and thiazide ... @priti899 #Hypokalemia
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... • Cell shift: Hypokalemic ... Loop diuretics, Thiazide ... syndrome #hypokalemia
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
Drugs Diuretics (thiazides ... Hypercalcemia, Hypokalemia ... antagonists (MRA) - Hyperkalemia ... higher risk of hyperkalemia ... - Pregnancy, Hyperkalemia
Hypophosphatemia - Differential Diagnosis Algorithm

Transcellular Shift
 • Recovery From DKA
 • Refeeding Syndrome
 • Acute Respiratory
Alkalosis • Hypokalemia ... Acetazolamide and Thiazide
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
gene that encodes thiazide-sensitive ... H+ secretion → Hypokalemia
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Malignancy True hypovolemia ... losses (especially thiazide