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diagnosis differential lupus ana antinuclear erythematosus management systemic antibody arthritis clinical hematology joint pain testing algorithm antibodies classification comparison cytoplasmic
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
: - SLE, SSc ... : - SjS, SLE, ... anti-Su/Ago • Golgi/polar ... : - SLE, SjS ... differential #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... erythematosus (SLE ... Antibodies #ANA #patterns ... #rheumatology #
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
Anti-phospholipid) M Malar ... #IMDAMNSHARP #sle ... erythematosus #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... Diseases: Lupus (SLE ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Manifestations: Malar ... are evocative of SLE ... management of SLE ... Management #Summary #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
B19 infection Malar ... rash • SLE ... IBD • RA • SLE ... erythematosus • SLE ... differential #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... & NPSLE rare, Malar ... Manifestations: Malar ... management of SLE ... comparison #table #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Arthritis 69% - Malar ... involvement 3% SLE-Related ... Lupusreference #SLE ... #differential #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Actinic damage - Solar ... Associated - SLE ... Differential #Diagnosis #hematology ... #rheumatology #
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Testing Cytoplasmic Patterns ... AMA Speckled: • SLE ... anti-Su/Ago Golgi/polar ... #Cytoplasmic #Patterns ... differential #diagnosis #rheumatology
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