14 results
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Albumin for Management ... • Acute kidney injury ... • Hepatorenal syndrome ... #Cirrhosis #treatment ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Toxic: Alcohol, Medication ... , Recreational Drugs ... obstruction, HELLP Syndrome ... Acute #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... duration), Several medications ... /HDS treatments ... disease, Hepatic ... #Algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injuryliver ... , HSV, VZV • Medications ... valproate, azoles), Drugs ... HELLP, Celiac disease ... #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... disease, liver ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... • Hepatorenal syndrome ... Treat underlying liver ... disease, ? ... + midodrine + albumin
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... Production: • Albumin ... disease: > 2 ... • Gilbert's syndrome ... #differential #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
) • Sepsis • Drug-induced ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... injury, though ... regarding need for treatment ... Diagnosis #Management #Hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Myeloproliferative disease ... • Nephrotic Syndrome ... , Ischemic Liver ... Vasculitis • Injury ... pathophysiology #hematology