12 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... duration), Several medications ... /HDS treatments ... disease, Hepatic ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... disease, liver ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Toxic: Alcohol, Medication ... , Recreational Drugs ... obstruction, HELLP Syndrome ... Causes #Acute #algorithm ... #hepatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... differential #diagnosis #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
, HSV, VZV • Medications ... valproate, azoles), Drugs ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Hepatitis • Drug ... #Causes #Hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Reaction to Medications ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... Blood Smear • Drugs ... • Pancreatic Disease ... Myelodysplastic Syndromes ... #Causes #Hematology