20 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... • Specific for SLE ... Treatment: • ... Systemic #Lupus #Erythematosus ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: • Acute ... Non-autoimmune rheumatologic ... Pleural effusions • Acute ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Evolution: Chronic disease ... lupus #Systemic #Erythematosus ... Management #Summary #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... AIP: acute interstitial ... rheumatoid arthritis SLE ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology #
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... with auto-immune diseases ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Advanced Liver Disease ... RA, SLE), Post-partum ... • Acute DIC - ... catastrophes, Acute ... Deficiencies #Summary #table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Evolution: Chronic disease ... #comparison #table ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... systemic lupus erythematosus ... [SLE], AOSD) • ... Treatment: • Corticosteroids ... #Rheumatology
NPSLE - Neurological and Psychiatric Manifestations of Systemic Lupus Erythematosus
 • Central: Aseptic meningitis, Cerebrovascular disease,
Systemic Lupus Erythematosus ... Cerebrovascular disease ... disorder, Myelopathy, Acute ... Systemic #Lupus #Erythematosus ... #SLE #rheumatology