12 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Supportive with treatment ... #SickleCell #Disease ... Hepatobiliary #hepatology ... #hepatitis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... underlying liver disease ... #Hepatology #gastroenterology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... /acute hepatitis ... • Infiltrative diseases ... Veno-occlusive disease ... Diagnosis #causes #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Cirrhosis ... - Alcoholic hepatitis ... fibrosis - Acute ... Causes #diagnosis #differential ... #hepatology #SAAG
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... malignancies Treatment ... Methotrexate • AIN ... #AKI #Cancer #Oncology ... #Differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... #differential # ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... Alcoholic liver disease ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Gradient (SAAG) - Differential ... >1.1 g/dl): - Cirrhosis ... - Alcoholic hepatitis ... - Acute fatty ... #Diagnosis #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... effusions, weight gain ... initiation • Differential ... Renal Failure Treatment ... #oncology
Carcinoembryonic antigen (CEA)
 • CEA is a highly glycosylated cell surface glycoprotein involved in intercellular adhesion
emphysema, Bronchitis, Acute ... Rectal polyps, Hepatitis ... , Alcoholic cirrhosis ... Smokers, Renal disease ... #differential #