22 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... Supportive with treatment ... #SickleCell #Disease ... Hepatobiliary #hepatology ... #hepatitis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... underlying liver disease ... #Hepatology #gastroenterology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Pancreatic Pseudocyst, Cancer ... Liver #Injury #Differential ... #algorithm #hepatology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... LC deposition disease ... malignancies Treatment ... Methotrexate • AIN ... #Oncology #Differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Cholestatic disease ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Pancreatic cancer ... Others #LFTs #Hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... /acute hepatitis ... • Infiltrative diseases ... Veno-occlusive disease ... Diagnosis #causes #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac disease ... Thrombocytosis #Platelets #Differential
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Cirrhosis ... - Alcoholic hepatitis ... fibrosis - Acute ... Causes #diagnosis #differential ... #hepatology #SAAG
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... #differential # ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
of cholestatic disease ... Alcoholic liver disease ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis