33 results
diagnosis management differential syndrome dermatology algorithm sle vasculitis classification erythematosus hairloss hemophagocytic lymphohistiocytosis oncology systemic blood cryoglobulinemia focal product reactions
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin Disease ... : Discoid lupus ... : Lupus erythematosus ... of any comorbid disease ... Prolactin, FSH, LH
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Congenital Diseases ... : • Systemic lupus ... erythematosus • HLH ... deficiency Infections ... Differential #Diagnosis #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Irreversible-biopsy required • Lupus ... Related • Post-infectious ... Secondary to Skin Disease ... • Discoid lupus ... Diagnosis #Algorithm #causes
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Framework Non-Infectious ... (RA), Systemic lupus ... , Sarcoidosis, HLA-B27 ... rare), Idiopathic Infectious ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Photosensitivity, Alopecia ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Diagnosis Algorithm Infectious ... Inflammatory • Systemic Lupus ... Diagnosis #Algorithm #Causes ... #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Myelofibrosis Infectious ... disorders • Celiac disease ... effect following treatment ... #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... #hematology
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