30 results
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology
Imaging Findings:
 • Ovoid hypointense structures along the bursal surface
- MSK Radiology ... consistent with Calcium ... adjacent to the Calcium ... • Treatment for ... Radiology #diagnosis #msk
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... of renal bone disease ... Calcium-containing ... the first-line treatments ... #Pharmacology #Pathophysiology
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
- Pathophysiology ... damage leading to calcium ... Calcium influx leads ... #Pathophysiology ... Complications #Hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... arthritides Crystal Deposition ... ochronosis and crystal deposition ... #Joint #Pain #MSK ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... Lysis Syndrome: • Pathophysiology ... • Treatment: ... diagnosis #management #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
HyperCalcemia- calcium ... ULN R - Renal disease ... ), light chain deposition ... and autoimmune diseases ... MGUS #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... Puncture, EEG Treatment ... CNS #neurology #rheumatology ... diagnosis #management #treatment
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Hypercalcemia (due to diseases ... Accumulation of calcium ... (GFR) -> decr ability ... Hyperuricemia #Pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Responsive to Treatment ... growth, response to treatment ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #summary #rheumatology