18 results
diagnosis differential nephrology pharmacology medications renal causes diuretics hyperkalemia acidosis pathophysiology potassium action algorithm discoloration rta stones table tubular urine
Thiazide diuretics Carbonic anhydrase inhibitors (e.g., acetazolamide) Nat-Cl symport Na and HCO;- reabsorption Aldosterone antagonists (e.g., spironolactone) Nat channel (indirect effect) Loop diuretics (e.g., furosemide) Amiloride, #triamterene Nat-K+-2CF symport Na channel (direct effect) #NaCI reabsorption
Amiloride, #triamterene
Mechanism of Action of Diuretics Amiloride, Triamterene, Spironolactone Loop Diuretics Thiazides Acetazolamide #Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Diuretics Amiloride, Triamterene
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
spironolactone, triamterene
Drugs causing hyperkalemia • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly •
Channel Blockers: Triamterene
Drugs that Impair Renal Potassium Excretion Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine Decreased Aldosterone Synthesis: Heparin,
function: Amiloride, Triamterene
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Eplerenone • Triamterene
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
blockers (Amiloride, Triamterene
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
Spironolactone - Triamterene
Renal Tubular Acidosis - Differential Diagnosis Algorithm Decreased Serum K, Urine pH < 5.5 - Proximal RTA Decreased
ENaC: Amiloride, Triamterene
Distal Renal Tubular Acidosis Distal RTA is the true Nephrogenic RTA and can be truly divided into
Amiloride and Triamterene
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