185 results
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Hair Loss (Alopecia ... Irreversible-biopsy required • Lupus ... • Androgenetic alopecia ... • Discoid lupus ... capitis • Trichotillomania
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
Localized Hair Loss (Alopecia ... • Discoid lupus ... Brocq • Alopecia ... capitis • Trichotillomania ... Absent • Alopecia
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
: • Scarring Alopecia ... Disease: Discoid lupus ... Tinea Capitis, Trichotillomania ... : Lupus erythematosus ... totalis, Alopecia
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... SUBACUTE CUTANEOUS LUPUS ... CHRONIC CUTANEOUS LUPUS ... - NON-SCARRING ALOPECIA
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... : Non-scarring alopecia ... cutaneous or discoid lupus ... Acute cutaneous lupus ... Class II or V lupus
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... areas -> Scaring alopecia ... mechanism) -> Alopecia ... Phenomenon #Lupus
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Photosensitivity, Alopecia ... , oral ulcers, Lupus ... Lupusreference #SLE #lupus
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
anything L - Lupus ... ulcers, arthritis, alopecia ... Could be lupus in
Secondary Disseminated Syphilis

Case from my residency that @EstradaElJefe helped me publish in JGIM. One important finding
is the patchy alopecia ... Photo #SkinRash #Alopecia
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Drug Induced Lupus ... Epidemiology: -10% of all lupus ... Photosensitivity, Alopecia ... , oral ulcers, Lupus