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differential management anemia hemolysis algorithm blood extravascular fever infectiousdiseases intravascular product reactions autoimmune babesia bacilliformis bartonella microbiology oroya rheumatology thromboticthrombocytopenicpurpura
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 1) DIAGNOSE AIHA ... C3d • Blood smear ... 2) LOOK FOR a cause ... #Anemia #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
- Differential Diagnosis ... Peripheral blood smear ... Infection mediated (Babesiosis ... #Differential #Diagnosis ... #Algorithm #causes
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... - Differential Diagnosis ... Membrane - Antibody ... #Differential #Diagnosis ... #Causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... Infections: Malaria, Babesiosis ... Extravascular #Causes ... #hematology #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential Diagnosis ... Malaria • Babesiosis ... #Algorithm #Causes ... #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... toxins: Malaria, Babesiosis ... Peripheral Blood Smear ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... decrease in most cases ... Peripheral blood smear ... #Workup #Hematology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... lysis → severe hemolytic ... Nodular → Mular DIAGNOSIS ... phase: Peripheral smear
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... Chagas disease), Babesiosis ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... Chagas disease), Babesiosis ... #Transfusions #diagnosis ... #management #hematology
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