21 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Pregnancy - TTP ... and Acute Fatty Liver ... child * Severe cases ... plasma exchange 2) TTP ... AFLP #obstetrics #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disease - DIC/TTP ... Defects: • DIC, TTP ... deficiency • Liver ... Differential #Diagnosis #hematology ... #rheumatology #
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Anemia Intrinsic Causes ... : • Liver disease ... Intravascular Causes ... : • MAHA: TTP, ... classification #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Hemolysis, Elevated Liver ... child * Severe cases ... exchange 2) Fatty liver ... of child 3) TTP ... Obstetrics #OBGyn #Hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... , vomiting, abdominal ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
: INR/PT, aPTT(liver ... bypass), LFT (liver ... or if a primary hematologic ... Refractory ITP, ... #Workup #hematology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... to cirrhosis, Abdominal ... Cirrhosis, Polycystic liver ... differential #diagnosis #causes ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... In liver, 80% of ... bile canaliculi (ATP-dependent ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
ileus), intra-abdominal ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus #
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperviscosity, TTP ... Syndrome, Ischemic Liver ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential