84 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... cell lysis → Release ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... Lysis -> Release ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... Lysis Syndrome: ... : Lysis of tumor ... #Lysis #Syndrome ... #TLS #diagnosis
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
- Differential Diagnosis ... Rhabdomyolysis • Tumor ... Lysis • Metabolic ... Hyperlipidemia • Tumor ... #Algorithm #endocrinology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... lysis kbs every ... #Lysis #Syndrome ... #diagnosis #management
Hypermagnesemia - Etiologies by Mechanism
Renal Failure 
Excessive Mg Administration 
 - Massive PO intake
Mechanisms - Tumor ... lysis syndrome ... #Differential #Diagnosis ... Table #Causes #Management
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
- Differential Diagnosis ... Tumor lysis syndrome ... #Differential #Diagnosis ... Algorithm #PTH #endocrinology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... acutekidneyinjury #Pathophysiology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
nephropathy • Solid tumors ... Capillary leak syndrome ... Interleukin-2) • Tumor ... lysis syndrome ... #Differential #Diagnosis
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
- Differential Diagnosis ... Hyperthecosis • Tumor ... Tumor Low Serum ... #Differential #Diagnosis ... #Algorithm #endocrinology