98 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology of Tumor ... Lysis Syndrome ... (TLS) Tumor Cell ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... Laboratory TLS ... #TumorLysis #Syndrome
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... ICU transfer • Tumor ... MatthewHoMD #TLS ... #Tumor #Lysis # ... Syndrome #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... Pathophysiology: Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Renin secreting tumor ... , Gitelman syndrom ... Differential #Diagnosis #Algorithm ... potassium #low #nephrology
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm
Radiculopathy:
 • Disc
 • Spondylosis
 •
Differential Diagnosis Algorithm ... Spondylosis • Tumor ... • Trauma • Tumor ... • Diabetes • Tumor ... Weakness #Sensory #Neurology
Gynecomastia - Differential Diagnosis Algorithm
No Testicular Mass on Ultrasound
 • Adrenal Neoplasm
 • Increased Extraglomerular Aromatase
Differential Diagnosis Algorithm ... • Leydig Cell Tumor ... • Sertoli Cell Tumor ... Klinefelter's Syndrome ... • Kallman's Syndrome
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Differential Diagnosis Algorithm ... Hyperthecosis • Tumor ... • Cushing's Syndrome ... Tumor Low Serum ... Differential #Diagnosis #Algorithm
Causes of Facial Weakness - Differential Diagnosis Algorithm
Forehead Sparing = Central cause
  - Most commonly
Differential Diagnosis Algorithm ... - Intracranial tumor ... Infection, Compression Tumor ... Differential #Diagnosis #Algorithm ... #Causes #neurology