11 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... La) - Sjogren's syndrome ... Anti-GBM - Goodpasture's ... #diagnosis #table ... #rheumatology #
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... : Jo-1, PL7, PL12 ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... associations - 1. ... of symptoms - 1- ... Urticaria #diagnosis #rheumatology ... #comparison #table
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Clinical Manifestations ... Mononucleosis-like disease ... Epstein—Barr virus EBV ... Microbiology #Diagnosis #Comparison ... #Table
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hodgkin's Lymphoma vs ... Non-Hodgkin's Lymphoma - Comparison ... • Clinical features ... (HIV, EN, HTLV-1, ... #NonHodgkins #comparison
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs ... to 1:1 F:M • Clinical ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... Anti-PCNA 1-5% ... erythematosus #diagnosis #rheumatology ... #table #ANA
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Antibodies: 1. ... Cold Agglutinin Syndrome ... Viral Infection Clinical ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... • Underlying disease ... • Metabolic syndrome ... #CPPD #Gout #Comparison ... #rheumatology #
Double Shunt on Echocardiogram
What do you see on this saline contrast study, in a patient with
end-stage liver disease ... 1. ... hepatopulmonary syndrome ... stretched PFO or ASD ... #clinical #pocus