33 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
is identical to ... microglobulin Treatment ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... transplant is only ... curative treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... anemia DDX: Rule Out ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Non-Hodgkin's Lymphoma - Comparison ... lymphoma that is ... #NonHodgkins #comparison ... #oncology #diagnosis ... #differential #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• 75% of ALL is ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD ... Kawasaki, Nephrotic syndrome
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Initial workup ... of the above Treatment ... • Tumor lysis kbs ... diagnosis #management #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... #oncology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
neuritis - Giant cell ... Nodules • RA • Gout ... Tophi - Gout ... pulses - Giant cell ... differential #diagnosis #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
marrow plasma cell ... • CML, B and T cell ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology