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diagnosis hematology management bowel gastroenterology ibs mds myelodysplastic algorithm anemia aplastic apml chronic classification cll criticalcare differential differentiation emergencies foamed
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... anemia DDX: Rule Out ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Irritable Bowel Syndrome (IBS) - Management Global IBS Symptoms: - Limited trial low FODMAP diet
Irritable Bowel ... Syndrome (IBS) - ... intestinal epithelial cells ... #Bowel #Syndrome ... gastroenterology #treatment
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel ... Syndrome (IBS) - ... for diagnosis Treatment ... intestinal epithelial cells ... #Bowel #Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... full infectious work-up ... days → add fungal work-up ... “big & sticky” cells ... ± tocilizumab; call
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... hormones that work ... Lactic Acidosis as well ... thiamine, and watch out ... for Refeeding Syndrome
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