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Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of ... Sites #Action #Nephron ... #Pharmacology # ... Nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Ketoacidosis: Diabetic ... oxoproline) • Renal ... Renal acidosis ... Generalized distal nephron ... #nephrology
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Diagnostic Approach to Hyperkalemia ... inhibitors Other causes ... cell disease - Renal ... Low Renin - Diabetes ... #differential #causes
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes ... Acquired - Primary renal ... uropathy, Metabolic causes ... (e.g., hypokalemia ... Classification #Types #Nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... (treatment of diabetic ... Villous adenoma Renal ... chewing tobacco, Renal ... #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Diagnosis Algorithm Hypovolemia ... wasting syndrome Hypovolemia ... Diagnosis #Algorithm #Causes ... #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... Correction of diabetic ... (steatorrhea) Renal ... Tubulointerstitial renal ... medications #drugs #pharmacology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Kidney stones caused ... Inhibitors of Renal ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Correction of diabetic ... steatorrhea) • Renal ... Tubulointerstitial renal ... differential #diagnosis #nephrology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... Diabetes, diabetic ... Renal resistance ... End-stage renal ... Classification #Causes