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Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... of Action Diuretics ... Adenosine #Nephron ... Sites #Action #nephrology
Renal Actions of Diuretics

#Diuretics #Sites #Action #Nephron #Pharmacology #Nephrology
Renal Actions of Diuretics ... #Diuretics # ... Sites #Action #Nephron ... #Pharmacology #Nephrology
Sites and Mechanisms of Action of Diuretics

#Diuretics #Nephron #SitesOfAction #Mechanism #Nephrology
Mechanisms of Action of Diuretics ... #Diuretics # ... Nephron #SitesOfAction ... #Mechanism #Nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Causes of High-anion ... Generalized distal nephron ... Potassium-sparing diuretics ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Renal tubular acidosis ... , Osmotic diuresis ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Renal losses, Diuretic ... with renal tubal acidosis ... Ketonuria, Osmotic diuresis ... #nephrology
Unmeasured Anions Associated with an Elevated Anion Gap and Metabolic Acidosis

#Unmeasured #Anions #Gap #Metabolic #Acidosis #Diagnosis
and Metabolic Acidosis ... Gap #Metabolic #Acidosis ... #Diagnosis #Nephrology ... #Differential #Causes
Diagnosis and Management of Hypernatremia

#Hypernatremia #Differential #Algorithm #Causes #Nephrology #Diagnosis

** GrepMed Recommended Text: Nephrology Secrets -
Diagnosis and Management ... Differential #Algorithm #Causes ... #Nephrology #Diagnosis ... Recommended Text: Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... Symport (Loop Diuretics ... Kidney stones caused ... #Nephrology #Pharmacology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
Causes of Hypomagnesemia ... Saline or osmotic diuresis ... • Drugs: Loop diuretics ... Hypomagnesemia #Causes ... differential #diagnosis #nephrology