Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 β€’ Iron deficiency
Diagnostic Framework ... Approach - MCV) Low ... Myelodysplastic syndrome ... #differential #diagnosis ... #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
Causes of Thrombocytosis ... - Differential Diagnosis ... malignancies β€’ Anemia ... Myelodysplastic syndrome ... #Causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #hematology #anemia
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
pressure - Normal/low ... Red blood cell casts ... Serum albumin - Low ... #Nephritic #Comparison ... #Diagnosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Elevated Liver tests, Low ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... Management #treatment #hematology
Causes of Pleural Effusion - Differential Diagnosis Algorithm
Transudate - Hydrostatic
 β€’ Congestive heart failure
 β€’ Constrictive
Causes of Pleural ... - Differential Diagnosis ... β€’ Asbestos β€’ Uremia ... #Algorithm #Hepatology ... #causes
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
approximately how ... infiltration (e.g ... Marrow suppression (e.g ... Production #Index #hematology ... #diagnosis #calculation
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Low in bone marrow ... of substrate (e.g ... . iron), low EPO ... #Workup #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... Hypocomplementemia #Low ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology