Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Microangiopathies In Systemic ... Erythematosus #SLE ... #hematology #rheumatology ... #differential #diagnosis ... #causes
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 β€’ Associated
Systemic Lupus Erythematosus ... block β€’ Sjogren syndrome ... polymyositis overlap syndrome ... #Summary #diagnosis ... #rheumatology #
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... common primary disease ... #Organs #Systems ... #Diagnosis #Hematology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... LungDisease #CTILD #Diagnosis ... Table #Pulmonary #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... antiphospholipid syndrome ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... #diagnosis #table ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 β€’ Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Evolution: Chronic disease ... #lupus #Systemic ... Management #Summary #rheumatology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
) Step 3: Is a Systemic ... Disease Prolonging ... to identify the cause ... APTT #prolonged #diagnosis ... #hematology #evaluation
Behcet's Syndrome - Treatment
Ulcers:
 β€’ Treatment: Topical steroids
 β€’ Prevention: Colchicine
 β€’ Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : β€’ Systemic steroids ... : β€’ Systemic steroids ... #Syndrome #Treatment ... #pharmacology #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... - Autoimmune: SLE ... antiphospholipid syndrome ... #Framework #hematology