Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of schistocytes / fragmentation hemolysis:
 β€’ Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... crisis β€’ Severe B12 ... deficiency β€’ Mechanical ... #schistocytes #differential ... #diagnosis #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... #Workup #Differential ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... #Workup #Differential ... #Hematology
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Underproduction Diagnostic ... disease - Vitamin B12 ... Underproduction #Algorithm #hematology ... #diagnosis #differential ... #workup
Red Blood Cell (RBC) Morphology Atlas
 β€’ Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology Atlas ... spherocytosis, Hemolytic ... #key #diagnosis ... #differential # ... hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 β€’ Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Macrocytic RBC: Vitamin B12 ... Microangiopathic Hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron deficiency ... loss), Vitamin B12 ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Etiologies of Folate Deficiency
 β€’ Decreased dietary intake - uncommon in this era
 β€’ Increased requirements
Etiologies of Folate Deficiency ... pregnant have hemolytic ... #FolicAcid #differential ... #diagnosis #hematology ... #nutrition
Etiologies of Vitamin B12 Deficiency
 β€’ Inadequate intake - Rare but seen in very strict vegans
Deficiency β€’ Inadequate ... deficiency. ... #differential # ... diagnosis #hematology ... #nutrition