Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... /nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Algorithm #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Syndrome == Nephrotic ... Red blood cell casts ... #Syndrome #Nephritic ... #Comparison #Table
Acute Kidney Injury (AKI) - Common Patterns on Urinalysis
 - Prerenal
 - ATN
 - AIN
 -
Acute Kidney Injury ... Syndrome - Nephritic ... Syndrome Dr. ... Urinalysis #diagnosis #table ... #comparison #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Diagnosis Algorithm Syndrome ... β€’ Drugs β€’ Pulmonary ... Cirrhosis β€’ Nephrotic ... Hypo-osmolar urine
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... β€’ Interstitial nephritis ... β€’ Cardio-renal syndrome ... #causes
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... are seen in acute ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... syndrome ("Maltese
Urine Microscopy - Casts
Acellular Casts
 β€’ Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of acute ... in a variety of acute ... suggestive of nephrotic ... sydnrome β€’ Pigment
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 β€’ Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Polyneuropathy, Acute ... stroke, Acute spinal ... Guillain-BarrΓ© syndrome ... differential #diagnosis #table ... #neurology
Hematuria Workup and Diagnosis Algorithm
 β€’ Confirm hematuria β†’ Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing β€’ Acute ... WBCs, or urine ... β†’ Urine culture ... proteinuria, RBC casts ... if cause not identified
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Simplified Approach to Acute ... require urgent nephrology ... Urinary obstruction, Nephrotoxic ... IMPROVEMENT If the urine ... LorinskyMD #AKI #Acute