Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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causes anemia hemolysis adultonset atlas b12 cd4 cirrhosis comparison defects disease extravascular g6pd hemolytic hepatology icl idiopathic inherited intravascular key
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... • Severe B12 deficiency ... anemia" • HELLP syndrome ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... specifically: iron deficiency ... Myelodysplastic syndrome ... #hematology #secondary
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Disease Clinical triad ... fraction < 20% Differential ... Diaqnoses: • ... mevalonate kinase deficiency ... management #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... G6PD deficiency) ... Extravascular #Causes #differential ... #diagnosis #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Grey Platelet Syndrome ... a storage pool deficiency ... comparison #table #differential ... #diagnosis #hematology
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
in Cirrhosis - Differential ... Diagnosis Framework ... bleed, Gastric antral ... Destruction: Zieve's syndrome ... #Diagnosis #Hepatology
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
patients with partial ... insufficiency, blind loops syndromes ... malabsorption syndromes ... #differential # ... diagnosis #hematology
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis - Chloroquine (Aralen)*
Patients with G6PD Deficiency ... Synthetase #G6PD #Deficiency ... #Medications #Differential ... #Diagnosis #Pharmacology ... #Hematology
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