Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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ANTIBIOTIC SUSCEPTIBILITIES IN INTENSIVE CARE

Antibiotic spectra made simple(r). Version 2, now updated with new bugs &
ANTIBIOTIC SUSCEPTIBILITIES ... INTENSIVE CARE Antibiotic ... #Classes #Bacterial ... CriticalCare #Overview #Pharmacology ... Comprehensive Review
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles - Antibiotics ... Class Overview ... hepatic, main toxicity ... Isavuconazole(PO or IV) #Pharmacology ... #Antibiotics #Review
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... Class Overview ... monitored to reduce toxicity ... #Pharmacology #Antibiotics ... #Review #Overview
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
Drug-Induced Seizures ... anticholinergics, amantadine, antibiotics ... Seizures #Medication #Causes ... #Differential #Pharmacology ... #Diagnosis #OTISCAMPBELL
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
blockers which cause ... widening #ECG #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential ... #Drugs #Classes
Etiologies of Peripheral Neuropathy
 β€’ Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 β€’ Medication-induced: ART, Antibiotics,
β€’ Medication-induced ... : ART, Antibiotics ... #differential #diagnosis ... #causes #neurology
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged ... Risperidone β€’ Antibiotics ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... Clozapine is known to cause ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 β€’
alcohol consumption Diagnostic ... therapy in severe cases ... Euglycemic #DKA #EDKA #Toxicity ... #Toxicology
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
Class Overview ... and 2) Does not cause ... no significant toxicity ... #Pharmacology #Antibiotics ... #Review #Overview