Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury ( ... PROBLEM ~80% of AKI cases ... for WBCs, RBCs, casts ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... white blood cell casts ... renal tubular cell casts ... or pigmented casts ... #Kidney #Injury
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
Causes of acute ... kidney injury (AKI ... #Diagnosis #AKI ... #Acute #Kidney # ... Injury #Differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... Acute Kidney Injury ... AKI - Differential ... Diagnosis HEMODYNAMIC ... Diagnosis #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... Diagnosis Baseline ... #Kidney #Injury ... Diagnosis #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... in a variety of acute ... and chronic kidney ... colored compounds (e.g ... interpretation #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... #Kidney #Injury ... Diagnosis #nephrology ... #causes #algorithm
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Polyneuropathy, Acute ... polyneuropathy (e.g ... #differential # ... diagnosis #table ... #neurology
Extrapulmonary manifestations of COVID-19
 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke
 • Renal:
of COVID-19 • Neurologic ... Stroke • Renal: Acute ... kidney injury, ... cor pulmonale ... Extrapulmonary #Diagnosis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... are seen in acute ... 34t5DgJ #Urinary #Casts