Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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diagnosis management hematology photo comparison hemophagocytic lymphohistiocytosis reactions syndrome differential eosinophilia hivaids idsa microscopy opportunistic pharmacology prevention product transfusion abnormal
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... accumulation of clinical ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... can mimic common infections ... : • Infection ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... associated with infection ... or autoimmune disease ... for refractory disease ... #hematology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
vasculitis - Diagnosis, causes ... cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... drug reaction, infection ... glucocorticoid treatment ... Differential #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... of high parity blood ... without other cause ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
high index of clinical ... in up to 30% of cases ... large infarct - Infectious ... Diseases Fellows ... Marantic #diagnosis #table
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... donors (due to anti-HLA ... Infection - Infection ... infections with ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... donors (due to anti-HLA ... • Infection - ... Infection occurs ... diagnosis #management #hematology
ED Treatment of Abnormal Uterine Bleeding Hemodynamically unstable Resuscitation • ABCs! • Fluids +
ED Treatment of ... • Fluids + blood ... pregnancy related cause ... increased risk of infection ... Hemodynamically stable
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