The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... Signs/Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... signs #symptoms #orthopedics
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... #Grades #Diagnosis ... #pathophysiology
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
other proteins leaking ... ischemia -> Venous beading ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... Alcohol withdrawal ... #Alcohol #Withdrawal ... #Pathophysiology ... #Diagnosis #Signs
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... of alcohol and/ ... #Opiate #Pathophysiology ... #Diagnosis #Signs
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
Signs/Symptoms/Complications ... TendonRupture #diagnosis ... signs #symptoms #pathophysiology ... #msk #orthopedics
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Clinical Features and Complications ... Grades #Grading #Orthopedics ... #MSK #diagnosis ... #complications ... #pathophysiology
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
- Tobacco & Alcohol ... #Stages #Orthopedics ... #msk #Staging # ... pathophysiology ... #diagnosis #disruptors
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Conductive hearing ... PagetsDisease #pathophysiology ... #diagnosis #signs