The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
BPD Mnemonic: AM SUICIDE ... instability - Suicide ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #AMSUICIDE
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... thoughts of death or suicide ... Pathophysiology #Signs
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
spinal cord - Signs ... Ataxia (early sign ... weakness (late sign ... dexterity loss (early signs ... Myelopathy #diagnosis #signs
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... • Spurling's sign ... pain Lasegue's sign ... MSK #diagnosis #signs
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... + Wartenbergs sign ... pathophysiology #signs
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
XR — scotty dog sign ... pathophysiology #signs
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... endocrinology #symptoms #signs
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... phase symptoms Signs ... immunology #diagnosis #signs
Central Retinal Vein Occlusion (CRVO): Pathogenesis and clinical findings

#CentralRetinalVein #Occlusion #CRVO #pathophysiology #ophthalmology #diagnosis #signs #symptoms
ophthalmology #diagnosis #signs
Giant Cell (Temporal) Arteritis: Clinical findings and Complications
Signs/Symptoms: 
 - Headache (usually constant, superimposed by waves
Complications Signs ... Complications #Signs