The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Major Depressive ... included in DSM 5 criteria ... partum onset) - Anxiety ... MajorDepressiveDisorder #Depression ... Pathophysiology #Signs
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
or stimuli • Avoidance ... maladaptive beliefs and anxiety ... Dysregulation of anxiety ... reduce obsessional anxiety ... Diagnosis #Psychiatry #Signs
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... of trauma • Avoidance ... diagnosis #symptoms #signs
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Experiential Avoidance ... • Avoidance of ... carrying anti-anxiety ... Anticipatory Anxiety ... diagnosis #symptoms #signs
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
maintain this state Depressive ... - Incr guilt, anxiety ... Pathophysiology #Signs
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
activities #AttentionDeficitHyperactiveDisorder ... diagnosis #symptoms #signs ... #psychiatry #criteria
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings
Cognitive-Perceptual
 • Magical thinking - Belief in paranormal or
anhedonia • Social Anxiety ... reference - Anxiety ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Avoidant Personality ... inferior #AVPD #Avoidant ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
Ex. agitated, avoiding ... Patient's subjective impression ... Observer's objective impression ... ideation -> Ex. anxiety
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
/ irritability/anxiety ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms