The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Third Generation Antipsychotics ... Antidepressant Effects #AntiPsychotics ... #pharmacology #diagnosis ... #psychiatry
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
of trauma • Avoidance ... Pathophysiology #diagnosis ... symptoms #signs #psychiatry
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Second Generation Antipsychotics ... Mechanism unknown #AntiPsychotics ... #pharmacology #diagnosis ... #psychiatry
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
Avoidant Personality ... inferior #AVPD #Avoidant ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings

Psychological Hypothesis
 • Cognitive behavioral model: Emotional disturbance arising from
or stimuli • Avoidance ... PersonalityDisorder #Diagnosis ... #Psychiatry #Signs
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
restlessness #AntiPsychotics ... #pharmacology #diagnosis ... #psychiatry
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings
 • Difficulties with Activities - Initiation Of projects
themselves • Avoidance ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... MoodDisorders #Diagnosis ... Signs #Symptoms #Psychiatry
Borderline Personality Disorder: Pathogenesis and Clinical Findings
Behavioral Traits:
 • Unstable Relationships - Alternating extremes of idealization
PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... Pathophysiology #diagnosis ... symptoms #signs #psychiatry ... #criteria