The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs pathophysiology psychiatry mnemonic personalitydisorder behavioraldisorder pediatrics growthhormone pituitary 21hydroxylasedeficiency 21ohd adhd amsuicide antisocial aspd attentiondeficithyperactivedisorder avoidant avpd borderline bpd
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... lipolysis Signs/Symptoms ... : • GH deficiency ... abn lipid • GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... suicide Other Symptoms ... MoodDisorders #Diagnosis ... Pathophysiology #Signs #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology ... #peds #pediatrics
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
findings - For diagnosis ... have either 26 symptoms ... to 25 for new diagnosis ... Pathophysiology #diagnosis ... #psychiatry #criteria
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... the above with symptoms ... PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
pathophysiology #diagnosis ... #symptoms #signs ... #peds #pediatrics
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings Cognitive-Perceptual • Magical thinking - Belief in paranormal or
PersonalityDisorder #Diagnosis ... #Psychiatry #Criteria ... #Signs #Symptoms
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