The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms pharmacology behavioraldisorder criteria sideeffects mnemonic anorexianervosa bulimianervosa etoh inhibitors lupus msk ophthalmology personalitydisorder retinopathy serotonin sle syndrome
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Dizziness - Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
decr intake -> Withdrawal ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry
Alcohol Use Disorder: Pathogenesis and Clinical Findings • Tolerance (reduced sensitivity to effects of EtOH) •
to use EtOH • Withdrawal ... , tachycardia, nausea ... Pathophysiology #Diagnosis ... Signs #Symptoms #Psychiatry
Opioid Withdrawal: Clinical Findings and Complications Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... Note: Opioid withdrawal ... Gastrointestinal distress (nausea ... Pathophysiology #Diagnosis
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
mood - Incr withdrawal ... MoodDisorders #Diagnosis ... Signs #Symptoms #Psychiatry
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Musculoskeletal #Complications ... signs #symptoms #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... Signs / Symptoms / Complications ... pathophysiology #geriatrics #diagnosis
Schizophrenia: Pathogenesis and Symptoms Increased dopaminergic transmission in mesolimbic projection -> Dopaminergic neurons here project into the limbic
is thought to cause ... is thought to cause ... pathophysiology #diagnosis ... symptoms #signs #psychiatry
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... disc arterioles causes ... ophthalmology #diagnosis ... signs #symptoms #complications
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