The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms complications fractures lupus adhesivecapsulitis aseptic caudaequina centralretinalartery classification crao differential disruptors erythematosus evaluation femur fracture frozenshoulder grades
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... Phenomenon #Lupus #SLE ... pathophysiology #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Myopathy (Also caused ... Erythematosus #SLE ... #MSK #Musculoskeletal ... signs #symptoms #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
a stroke that caused ... side) Second Stage ... movement) Third Stage ... pathophysiology #diagnosis ... #staging #msk
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... #orthopedics #diagnosis ... #differential #causes
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
Anterior Sl diastasis ... , posterior Sl ligaments ... posterior through Sl ... Grades #Grading #Orthopedics ... #MSK #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... pain (shooting, stabbing ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
GCA, SLE, GPA) - ... hypercoagulable state ... Hypercoagulable state ... retinal edema caused ... ophthalmology #diagnosis
Mental Status Exam (MSE) Note: The MSE is a "snapshot" of a patient at a specific time. You
Mental Status Exam ... (MSE) Note: The ... clothing, appears stated ... , the symptoms caused ... #psychiatry #diagnosis
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Inflammatory Stage ... Fluoroquinolones - Causes ... #Orthopedics #msk ... #Staging #pathophysiology ... #diagnosis #disruptors
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... Skull expansion causes ... pathophysiology #diagnosis
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