The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
palpation - Vasculitic ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... Complications #pathophysiology ... signs #symptoms #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Leukocytoclastic vasculitis ... #HSP #IgA #Vasculitis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification of ... PelvicRing #Fractures #Classification ... Orthopedics #MSK #diagnosis ... complications #pathophysiology
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Polymyositis #PM #Diagnosis ... #Pathophysiology ... Signs #Symptoms #Vasculitis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
CranialArteritis #Pathophysiology ... Signs #Symptoms #Diagnosis ... #Vasculitis
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Clinical Findings Diagnostic ... Disease #Criteria #Diagnosis ... #Pathophysiology ... Signs #Symptoms #Vasculitis