The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology psychiatry msk acute behavioraldisorder bulimianervosa lupus sle syndrome withdrawal adhd alcohol alzheimersdisease attentiondeficithyperactivedisorder caudaequina cecs centralretinalartery chronic chronicexertional closedangle
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
auto-reactive B and CD ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... / Symptoms / Complications ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... / Symptoms / Complications ... pathophysiology #diagnosis ... #symptoms #signs
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... BRB breakdown causes ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... /Symptoms/Complications ... #Signs #Symptoms
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• Significant cause ... most frequent cause ... damage & blindness Signs ... / Symptoms / Complications ... pathophysiology #ophthalmology
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
>18 years old, criteria ... weapon that can cause ... Pathophysiology #diagnosis ... #symptoms #signs ... #psychiatry #criteria
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... #symptoms #signs ... #psychiatry #criteria
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