The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Acne • Coarse features ... Overproduction #diagnosis ... signs #symptoms #endocrinology ... #pathophysiology
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
and Complications ... Grade 2 - Rami fracture ... Orthopedics #MSK #diagnosis ... #complications ... #pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... low energy fall fractures ... Major trauma -> An excess ... #orthopedics #diagnosis ... differential #causes #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Signs/Symptoms/Complications ... • Non-union of fracture ... #msk #diagnosis ... #pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
with psychotic features ... with psychotic features ... MoodDisorders #Diagnosis ... #Pathophysiology ... Signs #Symptoms #Psychiatry
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... bamboo spine) -> Fracture ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
increased risk of fracture ... - Lethargy or Excess ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Joint diseases features ... joint capsule exceeds ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... Symptoms related to complications ... BulimiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Calcification inhibitors (excess ... Bowed legs • Fractures ... #Osteomalacia #pathophysiology ... #diagnosis #signs