The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology symptoms lupus sle erythematosus extraarticular systemic ankylosingspondylitis criteria gastrointestinal kawasaki mucocutaneous musculoskeletal pagetsdisease popliteal ra rheumatoidarthritis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... interstitial lung disease ... pathophysiology #signs ... #symptoms #diagnosis
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... hands & feet Signs ... /Symptoms/Complications ... #Symptoms #Vasculitis
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings • Idiopathic • Meniscal Lesions • Osteoarthritis • Rheumatoid
underlying joint disease ... #Popliteal #BakersCyst ... #MSK #pathophysiology ... #signs #symptoms ... #diagnosis
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... Inflammatory Bowel Disease ... #Complications ... pathophysiology #diagnosis ... #signs #symptoms
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... Complications ... bone formation MSK ... pathophysiology #diagnosis ... #signs #symptoms
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