The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #symptoms #signs
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Fractures #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Subjective Tinnitus: Pathogenesis and clinical findings
Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... pathophysiology #differential ... #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... Fractures #msk #diagnosis ... pathophysiology #signs ... #symptoms #orthopedics
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk #orthopedics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... chromosome 21) Signs ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
#Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... pathophysiology #diagnosis ... #symptoms #signs