The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... Esp. humeral and femoral ... pathophysiology #signs ... #symptoms #diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
arthritis (RA) ... or systemic lupus ... / Symptoms: - ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
Giant Cell Arteritis ... Anemia of Chronic Disease ... Weight Loss #Temporal ... Pathophysiology #Signs ... #Symptoms #Diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
visual acuity • Bitemporal ... Cardiovascular disease ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... Pathogenesis and Joint diseases ... • Non-specific Acute-phase ... deviation, etc • Systemic ... #symptoms #diagnosis
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Takayasu’s Arteritis ... , Incr risk of Acute ... #Takayasus #Arteritis ... #Vasculitis #Diagnosis ... #Signs #Symptoms
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
CPPD) Deposition Disease ... - Acute CPPD ... polyarticular arthritis ... #Signs #Symptoms ... Pathophysiology #Diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
blood supply & the femoral ... - Sickle-cell disease ... affected) - Acute ... pathophysiology #diagnosis ... #signs #symptoms