The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs complications orthopedics sle erythematosus extraarticular ra rheumatoidarthritis systemic achilles ankylosingspondylitis anterior avascularnecrosis comparison degenerative dislocation gastrointestinal inflammatory injury jointdisease
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... -> Acute Pancreatitis ... #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Manifestations ... Livedo Reticularis, Vasculitis ... #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
swelling - GI Manifestations ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... TendonRupture #diagnosis ... #signs #symptoms ... #pathophysiology ... #msk #orthopedics
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... #Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics ... #pathophysiology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Injury #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Rheumatoid arthritis, Lupus ... Extra-articular manifestations ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Extra-articular manifestations ... • Non-specific Acute-phase ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis
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