The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms arteritis complications temporal giantcell lupus sle 21ohd cranialarteritis criteria dermatomyositis disease dm dysfunction endocin erectile erythematosus excess
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
a scrotum #21HydroxylaseDeficiency ... pathophysiology #genetics #endocrinology
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
palpation - Vasculitic ... Pathophysiology #Diagnosis ... Signs #Symptoms #Vasculitis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... Leukocytoclastic vasculitis ... Cutaneous small vessel vasculitis ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
the pancreas, Vasculitis ... signs #symptoms #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
pathophysiology #endocin #endocrinology ... symptoms #signs #diagnosis
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Signs #Symptoms #diagnosis ... #Vasculitis
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Overproduction #diagnosis ... signs #symptoms #endocrinology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Pathophysiology #Diagnosis ... Signs #Symptoms #Vasculitis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
blood vessels (vasculitis ... signs #symptoms #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Polymyositis #PM #Diagnosis ... Signs #Symptoms #Vasculitis
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