The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology menstrualcycle ovariancycle diagnosis pituitary feedbackloop gh growthhormone signs symptoms uterinecycle 21hydroxylasedeficiency 21ohd degenerative diabetes dka dysfunction endocin erectile excess
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
confusion coma #DiabeticKetoacidosis ... pathophysiology #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
pathophysiology #endocin #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
#FeedbackLoop #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
#FeedbackLoop #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
#menstruation #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
signs #symptoms #endocrinology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
pathophysiology #comparison ... #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
HypothalamicPituitary #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
pathophysiology #Ovulation #endocrinology
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