The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... #Pharmacology #SideEffects ... #Psychiatry #Diagnosis
Buproprion (Wellbutrin): Mechanisms and Side Effects
 • Adverse Effects: Headache, Dry Mouth, Weight loss, Insomnia, Constipation,
Epilepsy, Alcohol Withdrawal ... Benzodiazepine Withdrawal ... Buproprion #Wellbutrin #SideEffects ... #Pharmacology #Psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
decr intake -> Withdrawal ... MoodStabilizers #Mechanism #SideEffects ... Pathophysiology #Psychiatry
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
ThirdGeneration #Mechanisms #SideEffects ... #pharmacology #diagnosis ... #psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Signs / Symptoms / Complications ... #Macroadenoma #SideEffects ... #endocrinology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
to use EtOH • Withdrawal ... Pathophysiology #Diagnosis ... Signs #Symptoms #Psychiatry
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
mood - Incr withdrawal ... MoodDisorders #Diagnosis ... Signs #Symptoms #Psychiatry
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
SecondGeneration #Mechanisms #SideEffects ... #pharmacology #diagnosis ... #psychiatry
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... Clinical Findings and Complications ... Note: Opioid withdrawal ... combined with withdrawal ... Pathophysiology #Diagnosis