The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Treating DKA: 1) ... DiabeticKetoacidosis #DKA ... pathophysiology #endocrinology
Representative X-ray appearance of a primary malignant bone tumor - Ewings Sarcoma
 • "Interrupted periosteal reaction
LegXRay #Malignant #BoneTumor
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Metastatic bone tumors (aka ... bone tumor #BoneTumors
Representative X-ray appearance of a primary benign bone tumor - Aneurysmal Bone Cyst 
 • Soft
Labeled #Benign #BoneTumor
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
pathophysiology #endocin #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology
Malignant Bone Tumors: Clinical Findings and Complications

#Malignant #BoneTumors #Bony #Complications #pathophysiology
#Malignant #BoneTumors
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
#FeedbackLoop #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
#FeedbackLoop #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
#menstruation #endocrinology