The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology psychiatry msk complications criteria ophthalmology syndrome mnemonic personalitydisorder vasculitis behavioraldisorder orthopedics acute urology anorexianervosa arteritis bulimianervosa disease lupus
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... abn lipid • GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
spinal cord - Signs ... and Symptoms ... Ataxia (early sign ... weakness (late sign ... #symptoms #msk
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Radiculopathy: Signs and Symptoms • Back/Neck Pain • Decr Range of motion • Abnormal posturing •
Radiculopathy: Signs ... and Symptoms ... • Spurling's sign ... pain Lasegue's sign ... #symptoms #pathophysiology
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... and Symptoms Anaphylaxis ... Signs / Symptoms ... immunology #diagnosis #signs ... #symptoms
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... + Wartenbergs sign ... pathophysiology #signs ... #symptoms #msk
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
Complications Signs ... /Symptoms: - ... Stroke or TIA-like symptoms ... Complications #Signs ... #Symptoms #diagnosis
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