The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis symptoms signs menstrualcycle complications ovariancycle pediatrics msk ophthalmology orthopedics immunology pituitary anaphylaxis feedbackloop genetics gh growthhormone injury otitismedia retinopathy
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology ... #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
GravesDisease #pathophysiology ... #endocin #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... signs #symptoms #endocrinology ... #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
#21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
#FeedbackLoop #endocrinology ... #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Complications #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
Acute Otitis Media ... #OtitisMedia #pathophysiology ... symptoms #signs #peds
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... , Carditis #Acute ... RheumaticFever #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
#FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
#OvarianCycle #pathophysiology ... #menstruation #endocrinology
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