The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms orthopedics causes fractures adhesivecapsulitis agammaglobulinemia anterior cascade complications dislocation erythematosus femoralhead femur frozenshoulder gait immunity inflammation inflammatory
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Osteonecrosis Esp. humeral ... and femoral heads ... Erythematosus #SLE #MSK ... Complications #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Recruitment • Humoral ... #Inflammation #pathophysiology ... #immunology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Dislocation • Humeral ... Posterosuperior humeral ... Sachs Defect • Humeral ... signs #symptoms #msk ... #orthopedics #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... Impaction force from femoral ... bone from the femoral ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Humoral Immunity ... proliferate and differentiate ... repeat exposure #Humoral ... #Immunity #pathophysiology ... #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
deficiency in adaptive humoral ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
injury of Lateral Femoral ... MeralgiaParesthetica #MSK ... #pathophysiology ... #differential #
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Slipped capital femoral ... Trendelenburg #Gait #pathophysiology ... signs #diagnosis #msk
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Femur #Fractures #msk ... orthopedics #diagnosis #differential ... #causes #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
rotator cuff tear, humeral ... FrozenShoulder #pathophysiology ... stages #staging #msk
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