The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
masses of all sizes ... Signs / Symptoms ... • Hypothalamic dysfunction ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... Executive planning dysfunction ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vertigo, Sexual Dysfunction ... gain Incr NE: Nausea ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... bladder/bowel dysfunction ... pathophysiology #diagnosis ... #symptoms #signs
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
and hypothalamic-pituitary-adrenal ... sweating, trembling, nausea ... PanicDisorder #Anxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... their turn • Causes ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #symptoms #signs
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Compensatory muscular dysfunction ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
• Cognitive Symptoms ... flashes, headaches, nausea ... SocialAnxiety #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
physical fights • Uses ... weapon that can cause ... #Conduct #CD #BehavioralDisorder ... Pathophysiology #diagnosis ... #symptoms #signs